Guar Gum and Plasma Cholesterol
Effect of Guar Gum and an Oat Fiber Source on Plasma Lipoproteins and Cholesterol
in Hypercholesterolemic Adults
Spiller GA , Farquhar JW , Gates JE , Nichols SF
Health Research and Studies Center, Inc., Los Altos, CA
Arterioscler Thromb 1991 Sep-Oct;11(5):1204-8
Abstract: The hypolipidemic effect of guar gum (GG, 15 g/day) was compared with that of an oat fiber source (OFS, 77 g/day). Both treatments supplied the same amount of total dietary fiber (11g/day) and were taken with water three times a day for 3 weeks at mealtime. Thirteen free-living adult men and women participated in the study.
Their total plasma cholesterol (TC) was 244 +/- 21mg/dl (mean +/- SD), and plasma triglycerides (TGLYs) were 149 +/- 93 mg/dl before the intervention. Diets were monitored to ensure that no changes occurred other than the replacement of carbohydrate calories for the 200 kcal/day supplied by the OFS.
Combined averages for both of the crossover phases showed that GG induced a reduction in TC of 26 +/- 10 mg/dl and in low density lipoprotein cholesterol of 25 +/- 9 mg/dl. The OFS induced a reduction in TC of 9 +/- 13 mg/dl and in low density lipoprotein cholesterol of 11 +/- 4 mg/dl. Although both treatments were effective in reducing elevated TC, GG at the levels fed was significantly more effective (p less than 0.001) in reducing TC. Neither treatment induced significant changes in high density lipoprotein cholesterol or very low density lipoprotein cholesterol.
Note: The guar gum dietary fiber supplement used in this study is a patented product "Bios Life" manufactured and distributed by Unicity Network.
